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Pore opening and closing of a pentameric ligand-gated ion channel

Nerve signaling in humans and chemical sensing in bacteria both rely on the controlled opening and closing of the ion-conducting pore in pentameric ligand-gated ion channels. With the help of a multiscale simulation approach that combines mixed elastic network model calculations with molecular dynam...

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Detalhes bibliográficos
Main Authors: Zhu, Fangqiang, Hummer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993413/
https://ncbi.nlm.nih.gov/pubmed/21041674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009313107
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