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Pore opening and closing of a pentameric ligand-gated ion channel
Nerve signaling in humans and chemical sensing in bacteria both rely on the controlled opening and closing of the ion-conducting pore in pentameric ligand-gated ion channels. With the help of a multiscale simulation approach that combines mixed elastic network model calculations with molecular dynam...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993413/ https://ncbi.nlm.nih.gov/pubmed/21041674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009313107 |
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