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In vivo protein stabilization based on fragment complementation and a split GFP system

Protein stabilization was achieved through in vivo screening based on the thermodynamic linkage between protein folding and fragment complementation. The split GFP system was found suitable to derive protein variants with enhanced stability due to the correlation between effects of mutations on the...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lindman, Stina, Hernandez-Garcia, Armando, Szczepankiewicz, Olga, Frohm, Birgitta, Linse, Sara
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2010
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993370/
https://ncbi.nlm.nih.gov/pubmed/21041669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005689107
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