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Disruption of adenylyl cyclase type V does not rescue the phenotype of cardiac-specific overexpression of G(αq) protein-induced cardiomyopathy
Adenylyl cyclase (AC) is the principal effector molecule in the β-adrenergic receptor pathway. AC(V) and AC(VI) are the two predominant isoforms in mammalian cardiac myocytes. The disparate roles among AC isoforms in cardiac hypertrophy and progression to heart failure have been under intense invest...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993201/ https://ncbi.nlm.nih.gov/pubmed/20709863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01208.2009 |
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