Adenylyl Cyclase Subtype-Specific Compartmentalization: Differential Regulation of L-type Ca(2+) Current in Ventricular Myocytes

RATIONALE: Adenylyl cyclase (AC) represents one of the principal molecules in the β-adrenergic receptor (βAR) signaling pathway, responsible for the conversion of ATP to the second messenger, cAMP. AC type 5 (ACV) and 6 (ACVI) are the two main isoforms in the heart. While highly homologous in sequen...

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Detalhes bibliográficos
Main Authors: Timofeyev, Valeriy, Myers, Richard E., Kim, Hyo Jeong, Woltz, Ryan L., Sirish, Padmini, Heiserman, James P., Li, Ning, Singapuri, Anil, Tang, Tong, Yarov-Yarovoy, Vladimir, Yamoah, Ebenezer N., Hammond, H. Kirk, Chiamvimonvat, Nipavan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751398/
https://ncbi.nlm.nih.gov/pubmed/23609114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.300370
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