Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

A DNA-transfection protocol has been developed that makes use of a synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTMA). Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of the DNA...

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Detalhes bibliográficos
Main Authors: Felgner, P L, Gadek, T R, Holm, M, Roman, R, Chan, H W, Wenz, M, Northrop, J P, Ringold, G M, Danielsen, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299306/
https://ncbi.nlm.nih.gov/pubmed/2823261
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