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Structural Requirements for Activation in αIIbβ3 Integrin
Integrins are postulated to undergo structural rearrangement from a low affinity bent conformer to a high affinity extended conformer upon activation. However, some reports have shown that a bent conformer is capable of binding a ligand, whereas another report has shown that integrin extension does...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992275/ https://ncbi.nlm.nih.gov/pubmed/20884611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.139667 |
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