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Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit.

Chemical or enzymic reduction/oxidation of integrin cysteine residues (e.g. by reducing agents and protein disulphide isomerase) may be a mechanism for regulating integrin function. It has also been proposed that unique cysteine residues in the integrin beta3 subunit are involved in the regulation o...

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Détails bibliographiques
Auteurs principaux: Kamata, Tetsuji, Ambo, Hironobu, Puzon-McLaughlin, Wilma, Tieu, Kenneth Khiem, Handa, Makoto, Ikeda, Yasuo, Takada, Yoshikazu
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224037/
https://ncbi.nlm.nih.gov/pubmed/14690453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031701
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