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Intracellular Activation of Interferon Regulatory Factor-1 by Nanobodies to the Multifunctional (Mf1) Domain

IRF-1 is a tumor suppressor protein that activates gene expression from a range of promoters in response to stimuli spanning viral infection to DNA damage. Studies on the post-translational regulation of IRF-1 have been hampered by a lack of suitable biochemical tools capable of targeting the endoge...

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Detalhes bibliográficos
Main Authors: Möller, Angeli, Pion, Emmanuelle, Narayan, Vikram, Ball, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992268/
https://ncbi.nlm.nih.gov/pubmed/20817723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149476
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