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Cooperative Regulation of the Interferon Regulatory Factor-1 Tumor Suppressor Protein by Core Components of the Molecular Chaperone Machinery

Our understanding of the post-translational processes involved in regulating the interferon regulatory factor-1 (IRF-1) tumor suppressor protein is limited. The introduction of mutations within the C-terminal Mf1 domain (amino acids 301–325) impacts on IRF-1-mediated gene repression and growth suppr...

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Hlavní autoři: Narayan, Vikram, Eckert, Mirjam, Zylicz, Alicja, Zylicz, Maciej, Ball, Kathryn L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757990/
https://ncbi.nlm.nih.gov/pubmed/19502235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019505
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