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Interferon Regulatory Factor 1 Binding to p300 Stimulates DNA-Dependent Acetylation of p53
Interferon regulatory factor 1 (IRF-1) and p53 control distinct sets of downstream genes; however, these two antioncogenic transcription factors converge to regulate p21 gene expression and to inhibit tumor formation. Here we investigate the mechanism by which IRF-1 and p53 synergize at the p21 prom...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525491/ https://ncbi.nlm.nih.gov/pubmed/15509808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.10083-10098.2004 |
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