The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7: ROLES OF RECEPTOR DOMAINS

CXCR7 is an atypical chemokine receptor that signals through β-arrestin in response to agonists without detectable activation of heterotrimeric G-proteins. Its cognate chemokine ligand CXCL12 also binds CXCR4, a chemokine receptor of considerable clinical interest. Here we report that TC14012, a pep...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Gravel, Stéphanie, Malouf, Camille, Boulais, Philip E., Berchiche, Yamina A., Oishi, Shinya, Fujii, Nobutaka, Leduc, Richard, Sinnett, Daniel, Heveker, Nikolaus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992227/
https://ncbi.nlm.nih.gov/pubmed/20956518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.147470
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items