Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.

Progressive amyloid deposition in senile plaques and cortical blood vessels may play a central role in the pathogenesis of Alzheimer disease. We have used x-ray diffraction and electron microscopy to study the molecular organization and morphology of macromolecular assemblies formed by three synthet...

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Main Authors: Kirschner, D A, Inouye, H, Duffy, L K, Sinclair, A, Lind, M, Selkoe, D J
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1987
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC299203/
https://ncbi.nlm.nih.gov/pubmed/3477820
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