Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.
Progressive amyloid deposition in senile plaques and cortical blood vessels may play a central role in the pathogenesis of Alzheimer disease. We have used x-ray diffraction and electron microscopy to study the molecular organization and morphology of macromolecular assemblies formed by three synthet...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1987
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3477820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.19.6953 |
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