Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Primary malignant gliomas from 63 patients were analyzed to determine the relationship between amplification of the gene encoding the epidermal growth factor receptor (EGFR) and expression of the corresponding mRNA. Twenty-four tumors were found to have amplified the EGFR gene and amplification of o...

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Bibliografische gegevens
Hoofdauteurs: Wong, A J, Bigner, S H, Bigner, D D, Kinzler, K W, Hamilton, S R, Vogelstein, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1987
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299192/
https://ncbi.nlm.nih.gov/pubmed/3477813
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