Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Primary malignant gliomas from 63 patients were analyzed to determine the relationship between amplification of the gene encoding the epidermal growth factor receptor (EGFR) and expression of the corresponding mRNA. Twenty-four tumors were found to have amplified the EGFR gene and amplification of o...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Wong, A J, Bigner, S H, Bigner, D D, Kinzler, K W, Hamilton, S R, Vogelstein, B
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1987
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3477813/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.19.6899
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