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Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.

We have investigated human gliomas that amplify and rearrange the epidermal growth factor receptor gene, with generation of an in-frame deletion mutation of 802 nucleotides in the external domain. This in-frame deletion mutation generates a local amino acid sequence at the fusion junction of what no...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Humphrey, P A, Wong, A J, Vogelstein, B, Zalutsky, M R, Fuller, G N, Archer, G E, Friedman, H S, Kwatra, M M, Bigner, S H, Bigner, D D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1693434/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4207
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