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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity.

The development and neoplastic progression of human astrocytic tumors appears to result through an accumulation of genetic alterations occurring in a relatively defined order. One such alteration is amplification of the epidermal growth factor receptor (EGFR) gene. This episomal amplification occurs...

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Detalhes bibliográficos
Main Authors: Nishikawa, R, Ji, X D, Harmon, R C, Lazar, C S, Gill, G N, Cavenee, W K, Huang, H J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44475/
https://ncbi.nlm.nih.gov/pubmed/8052651
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