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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity.

The development and neoplastic progression of human astrocytic tumors appears to result through an accumulation of genetic alterations occurring in a relatively defined order. One such alteration is amplification of the epidermal growth factor receptor (EGFR) gene. This episomal amplification occurs...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Nishikawa, R, Ji, X D, Harmon, R C, Lazar, C S, Gill, G N, Cavenee, W K, Huang, H J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44475/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7727
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