Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector.

We have constructed a vaccinia virus recombinant that expresses the extracellular domain of the rat neu oncogene-encoded protein, a 185-kDa transmembrane glycoprotein termed p185. Strain NFS mice immunized with this recombinant virus developed a strong antibody response against the neu oncogene prod...

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Detalles Bibliográficos
Autores principales: Bernards, R, Destree, A, McKenzie, S, Gordon, E, Weinberg, R A, Panicali, D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC299183/
https://ncbi.nlm.nih.gov/pubmed/3477812
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