Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector.
We have constructed a vaccinia virus recombinant that expresses the extracellular domain of the rat neu oncogene-encoded protein, a 185-kDa transmembrane glycoprotein termed p185. Strain NFS mice immunized with this recombinant virus developed a strong antibody response against the neu oncogene prod...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1987
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3477812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.19.6854 |
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