Generation of hybrid genes and proteins by vaccinia virus-mediated recombination: application to human immunodeficiency virus type 1 env.

The ability of poxviruses to undergo intramolecular recombination within tandemly arranged homologous sequences can be used to generate chimeric genes and proteins. Genes containing regions of nucleotide homology will recombine to yield a single sequence composed of portions of both original genes....

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Publié dans:	J Virol
Auteurs principaux:	Gritz, L, Destree, A, Cormier, N, Day, E, Stallard, V, Caiazzo, T, Mazzara, G, Panicali, D
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2243381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.5948-5957.1990
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