Generation of hybrid genes and proteins by vaccinia virus-mediated recombination: application to human immunodeficiency virus type 1 env.

The ability of poxviruses to undergo intramolecular recombination within tandemly arranged homologous sequences can be used to generate chimeric genes and proteins. Genes containing regions of nucleotide homology will recombine to yield a single sequence composed of portions of both original genes....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gritz, L, Destree, A, Cormier, N, Day, E, Stallard, V, Caiazzo, T, Mazzara, G, Panicali, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2243381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.5948-5957.1990
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