Generation of hybrid genes and proteins by vaccinia virus-mediated recombination: application to human immunodeficiency virus type 1 env.

The ability of poxviruses to undergo intramolecular recombination within tandemly arranged homologous sequences can be used to generate chimeric genes and proteins. Genes containing regions of nucleotide homology will recombine to yield a single sequence composed of portions of both original genes....

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Bibliographic Details
Main Authors: Gritz, L, Destree, A, Cormier, N, Day, E, Stallard, V, Caiazzo, T, Mazzara, G, Panicali, D
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC248768/
https://ncbi.nlm.nih.gov/pubmed/2243381
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