Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector.

We have constructed a vaccinia virus recombinant that expresses the extracellular domain of the rat neu oncogene-encoded protein, a 185-kDa transmembrane glycoprotein termed p185. Strain NFS mice immunized with this recombinant virus developed a strong antibody response against the neu oncogene prod...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Bernards, R, Destree, A, McKenzie, S, Gordon, E, Weinberg, R A, Panicali, D
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3477812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.19.6854
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