Accurate modification of a chromosomal plasmid by homologous recombination in human cells.

We have examined the consequences of modifying mammalian cellular DNA sequences by homologous recombination. A plasmid carrying a 248-base-pair deletion in the neomycin phosphotransferase (neo) gene was introduced into hamster and human cells. The integrated, defective neo gene was used as a target...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Song, K Y, Schwartz, F, Maeda, N, Smithies, O, Kucherlapati, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC299176/
https://ncbi.nlm.nih.gov/pubmed/2821545
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky