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Accurate modification of a chromosomal plasmid by homologous recombination in human cells.

We have examined the consequences of modifying mammalian cellular DNA sequences by homologous recombination. A plasmid carrying a 248-base-pair deletion in the neomycin phosphotransferase (neo) gene was introduced into hamster and human cells. The integrated, defective neo gene was used as a target...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Song, K Y, Schwartz, F, Maeda, N, Smithies, O, Kucherlapati, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1987
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC299176/
https://ncbi.nlm.nih.gov/pubmed/2821545
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