Accurate modification of a chromosomal plasmid by homologous recombination in human cells.

We have examined the consequences of modifying mammalian cellular DNA sequences by homologous recombination. A plasmid carrying a 248-base-pair deletion in the neomycin phosphotransferase (neo) gene was introduced into hamster and human cells. The integrated, defective neo gene was used as a target...

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Detaylı Bibliyografya
Asıl Yazarlar: Song, K Y, Schwartz, F, Maeda, N, Smithies, O, Kucherlapati, R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1987
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC299176/
https://ncbi.nlm.nih.gov/pubmed/2821545
Etiketler: Etiketle
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