Cholesterol, a Major Component of Caveolae, Down-regulates Matrix Metalloproteinase-1 Expression through ERK/JNK Pathway in Cultured Human Dermal Fibroblasts

BACKGROUND: Cholesterol is a major component of specialized membrane microdomains known as lipid rafts or caveolae, which modulate the fluidity of biological membranes. Membrane cholesterol therefore plays an important role in cell signaling and vesicular transport. OBJECTIVE: In this study, we inve...

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Hlavní autoři: Kim, Sangmin, Han, Jeonghun, Lee, Dong Hun, Cho, Kwang Hyun, Kim, Kyu Han, Chung, Jin Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991713/
https://ncbi.nlm.nih.gov/pubmed/21165206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2010.22.4.379
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