Cholesterol, a Major Component of Caveolae, Down-regulates Matrix Metalloproteinase-1 Expression through ERK/JNK Pathway in Cultured Human Dermal Fibroblasts

BACKGROUND: Cholesterol is a major component of specialized membrane microdomains known as lipid rafts or caveolae, which modulate the fluidity of biological membranes. Membrane cholesterol therefore plays an important role in cell signaling and vesicular transport. OBJECTIVE: In this study, we inve...

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Main Authors: Kim, Sangmin, Han, Jeonghun, Lee, Dong Hun, Cho, Kwang Hyun, Kim, Kyu Han, Chung, Jin Ho
Formáid: Artigo
Teanga:Inglês
Foilsithe: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2010
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991713/
https://ncbi.nlm.nih.gov/pubmed/21165206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2010.22.4.379
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