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Methylglyoxal-derived advanced glycation end products induce matrix metalloproteinases through activation of ERK/JNK/NF-κB pathway in kidney proximal epithelial cells

The accumulation of reactive α-dicarbonyl leading to advanced glycation end products (AGEs) have been linked to pathophysiological diseases in many studies, such as atherosclerosis, cataract, cancer, and diabetic nephropathy. Glycation-generated AGEs increase the expression of inflammatory cytokines...

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Publicat a:Food Sci Biotechnol
Autors principals: Jeong, So-Ra, Park, Ho-Young, Kim, Yoonsook, Lee, Kwang-Won
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221093/
https://ncbi.nlm.nih.gov/pubmed/32419966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10068-019-00704-7
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