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Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

INTRODUCTION: Oestrogen depletion may influence onset and/or progression of osteoarthritis. We investigated in an ovariectomized mouse model the impact of oestrogen loss and oestrogen supplementation on articular cartilage and subchondral bone in tibia and patella, and assessed bone changes in osteo...

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Bibliografiske detaljer
Main Authors: Sniekers, Yvonne H, Weinans, Harrie, van Osch, Gerjo JVM, van Leeuwen, Johannes PTM
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991014/
https://ncbi.nlm.nih.gov/pubmed/20923566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3148
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