Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

INTRODUCTION: Oestrogen depletion may influence onset and/or progression of osteoarthritis. We investigated in an ovariectomized mouse model the impact of oestrogen loss and oestrogen supplementation on articular cartilage and subchondral bone in tibia and patella, and assessed bone changes in osteo...

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Main Authors: Sniekers, Yvonne H, Weinans, Harrie, van Osch, Gerjo JVM, van Leeuwen, Johannes PTM
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991014/
https://ncbi.nlm.nih.gov/pubmed/20923566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3148
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