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Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis

INTRODUCTION: Oestrogen depletion may influence onset and/or progression of osteoarthritis. We investigated in an ovariectomized mouse model the impact of oestrogen loss and oestrogen supplementation on articular cartilage and subchondral bone in tibia and patella, and assessed bone changes in osteo...

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Detalhes bibliográficos
Main Authors: Sniekers, Yvonne H, Weinans, Harrie, van Osch, Gerjo JVM, van Leeuwen, Johannes PTM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991014/
https://ncbi.nlm.nih.gov/pubmed/20923566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3148
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