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Impact of translational error-induced and error-free misfolding on the rate of protein evolution
What determines the rate of protein evolution is a fundamental question in biology. Recent genomic studies revealed a surprisingly strong anticorrelation between the expression level of a protein and its rate of sequence evolution. This observation is currently explained by the translational robustn...
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Format: | Artigo |
Jezik: | Inglês |
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Nature Publishing Group
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990641/ https://ncbi.nlm.nih.gov/pubmed/20959819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.78 |
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