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Determinants of the rate of protein sequence evolution

The rate and mechanism of protein sequence evolution have been central questions in evolutionary biology since the 1960s. Although the rate of protein sequence evolution depends primarily on the level of functional constraint, exactly what constitutes functional constraint has remained unclear. The...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Zhang, Jianzhi, Yang, Jian-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523088/
https://ncbi.nlm.nih.gov/pubmed/26055156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3950
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