Local Packing Density Is the Main Structural Determinant of the Rate of Protein Sequence Evolution at Site Level

Functional and biophysical constraints result in site-dependent patterns of protein sequence variability. It is commonly assumed that the key structural determinant of site-specific rates of evolution is the Relative Solvent Accessibility (RSA). However, a recent study found that amino acid substitu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yeh, So-Wei, Huang, Tsun-Tsao, Liu, Jen-Wei, Yu, Sung-Huan, Shih, Chien-Hua, Hwang, Jenn-Kang, Echave, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119917/
https://ncbi.nlm.nih.gov/pubmed/25121105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/572409
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados