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Too packed to change: side-chain packing and site-specific substitution rates in protein evolution

In protein evolution, due to functional and biophysical constraints, the rates of amino acid substitution differ from site to site. Among the best predictors of site-specific rates are solvent accessibility and packing density. The packing density measure that best correlates with rates is the weigh...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PeerJ
Prif Awduron: Marcos, María Laura, Echave, Julian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: PeerJ Inc. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411540/
https://ncbi.nlm.nih.gov/pubmed/25922797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.911
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