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Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution
The biological causes of selective pressures on coding-sequence evolution remain controversial, despite the surprising consistency of covariation between common measures of evolutionary change (substitution rates) and gene expression (mRNA levels, codon usage) across taxa. We carry out a unified ana...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696314/ https://ncbi.nlm.nih.gov/pubmed/18662548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.042 |
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