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Plk4/SAK/ZYG-1 in the regulation of centriole duplication

Centrioles organize both centrosomes and cilia. Centriole duplication is tightly regulated and coordinated with the cell cycle to limit duplication to only once per cell cycle. Defects in centriole number and structure are commonly found in cancer. Plk4/SAK and the functionally related Caenorhabditi...

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Detalles Bibliográficos
Main Authors: Pearson, Chad G, Winey, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Faculty of 1000 Ltd 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990628/
https://ncbi.nlm.nih.gov/pubmed/21173875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-58
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