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Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication
In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is critical. The C. elegans homolog of Plk4, ZYG-1, is required for centriole duplication, but our understanding of how ZYG-1 levels are regulated...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5289615/ https://ncbi.nlm.nih.gov/pubmed/28103229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006543 |
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