The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels

The correct segregation of DNA during cell division requires formation of a bipolar spindle, organized at each pole by a centrosome. The regulation of centrosome duplication such that each mitotic cell has exactly two centrosomes is therefore of central importance to cell division. Deregulation of c...

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Bibliographic Details
Main Authors: Peel, Nina, Dougherty, Michael, Goeres, Jacqueline, Liu, Yan, O'Connell, Kevin F.
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445323/
https://ncbi.nlm.nih.gov/pubmed/22623721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.097105
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