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Everything in moderation: Proteolytic regulation of centrosome duplication

The presence of too many or too few centrosomes at mitosis can disrupt the timely formation of a bipolar spindle and may lead to aneuploidy and cancer. Strict control of centrosome duplication is therefore crucial. Centrosome duplication must occur once per cell cycle and the number of new centriole...

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Autore principale: Peel, Nina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704442/
https://ncbi.nlm.nih.gov/pubmed/24058868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/worm.22497
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