Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

Centrosomes organize the mitotic spindle to ensure accurate segregation of the chromosomes in mitosis. The mechanism that ensures accurate duplication and separation of the centrosomes underlies the fidelity of chromosome segregation, but remains unknown. In Saccharomyces cerevisiae, entry into S ph...

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Main Authors: Freed, Ellen, Lacey, Kathleen R., Huie, Philip, Lyapina, Svetlana A., Deshaies, Raymond J., Stearns, Tim, Jackson, Peter K.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1999
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC316987/
https://ncbi.nlm.nih.gov/pubmed/10485847
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