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Mammalian microRNAs predominantly act to decrease target mRNA levels
MicroRNAs (miRNAs) are endogenous ∼22-nucleotide RNAs that play important gene-regulatory roles by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translational efficiency and/or decreased mRNA levels, but the relativ...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990499/ https://ncbi.nlm.nih.gov/pubmed/20703300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09267 |
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