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Predicting effective microRNA target sites in mammalian mRNAs

MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical sites are equally effective, and both computational and in vivo UV-crosslinking approaches suggest that many mRNAs are targeted through non-...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Agarwal, Vikram, Bell, George W, Nam, Jin-Wu, Bartel, David P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532895/
https://ncbi.nlm.nih.gov/pubmed/26267216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05005
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