mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues

MicroRNAs (miRNAs) regulate target mRNAs through a combination of translational repression and mRNA destabilization, with mRNA destabilization dominating at steady state in the few contexts examined globally. Here, we extend the global steady-state measurements to additional mammalian contexts and f...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Eichhorn, Stephen W., Guo, Huili, McGeary, Sean E., Rodriguez-Mias, Ricard A., Shin, Chanseok, Baek, Daehyun, Hsu, Shu-hao, Ghoshal, Kalpana, Villén, Judit, Bartel, David P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292926/
https://ncbi.nlm.nih.gov/pubmed/25263593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.08.028
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