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mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues
MicroRNAs (miRNAs) regulate target mRNAs through a combination of translational repression and mRNA destabilization, with mRNA destabilization dominating at steady state in the few contexts examined globally. Here, we extend the global steady-state measurements to additional mammalian contexts and f...
में बचाया:
में प्रकाशित: | Mol Cell |
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मुख्य लेखकों: | , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292926/ https://ncbi.nlm.nih.gov/pubmed/25263593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.08.028 |
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