A carregar...
Complete deletion of Apc results in severe polyposis in mice
The adenomatous polyposis coli (APC) gene product is mutated in the vast majority of human colorectal cancer. APC negatively regulates the WNT pathway by aiding in the degradation of β-Catenin, the transcription factor activated downstream of WNT signaling. APC mutations result in β-Catenin stabiliz...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990498/ https://ncbi.nlm.nih.gov/pubmed/20010873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.457 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|