Mouse CD8α(+) DCs and human BDCA3(+) DCs are major producers of IFN-λ in response to poly IC

Polyinosinic:polycytidylic acid (poly IC), a double-stranded RNA, is an effective adjuvant in vivo. IFN-λs (also termed IL-28/29) are potent immunomodulatory and antiviral cytokines. We demonstrate that poly IC injection in vivo induces large amounts of IFN-λ, which depended on hematopoietic cells a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lauterbach, Henning, Bathke, Barbara, Gilles, Stefanie, Traidl-Hoffmann, Claudia, Luber, Christian A., Fejer, György, Freudenberg, Marina A., Davey, Gayle M., Vremec, David, Kallies, Axel, Wu, Li, Shortman, Ken, Chaplin, Paul, Suter, Mark, O’Keeffe, Meredith, Hochrein, Hubertus
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989774/
https://ncbi.nlm.nih.gov/pubmed/20975040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092720
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker