Structure of the Anaphase-Promoting Complex/Cyclosome Interacting with a Mitotic Checkpoint Complex

Once all chromosomes are connected to the mitotic spindle (bioriented), anaphase is initiated by the protein ubiquitylation activity of the anaphase-promoting complex/cyclosome (APC/C) and its coactivator Cdc20 (APC/C(Cdc20)). Before chromosome biorientation, anaphase is delayed by a mitotic checkpo...

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Hlavní autoři: Herzog, Franz, Primorac, Ivana, Dube, Prakash, Lenart, Peter, Sander, Björn, Mechtler, Karl, Stark, Holger, Peters, Jan-Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989460/
https://ncbi.nlm.nih.gov/pubmed/19286556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163300
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