5′-Single-stranded/duplex DNA junctions are loading sites for E. coli UvrD translocase

Escherichia coli UvrD is a 3′–5′ superfamily 1A helicase/translocase involved in a variety of DNA metabolic processes. UvrD can function either as a helicase or only as an single-stranded DNA (ssDNA) translocase. The switch between these activities is controlled in vitro by the UvrD oligomeric state...

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Main Authors: Tomko, Eric J, Jia, Haifeng, Park, Jeehae, Maluf, Nasib K, Ha, Taekjip, Lohman, Timothy M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2010
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989100/
https://ncbi.nlm.nih.gov/pubmed/20877334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.242
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